Perinatal Outcome of Intrahepatic Cholestasis of Pregnancy

Objective: To determine the perinatal outcome of intrahepatic cholestasis pregnancy and its association with obstetric biochemical parameters.
 Study Design: cross-sectional study.
 Place Duration Study: Pak Emirates Military Hospital, Rawalpindi, from Feb to Aug 2020.
 Methodology: Among 3201 patients, 50 patients were included in study. Data was collected on a well-designed proforma. Patients’ characteristics such as age, parity, gestational age at diagnosis delivery, mode delivery co-morbidities taken along markers. Two groups made based outcome, associations all variables checked.
 Results: Obstetric found be 1.6%. The mean subjects 27.36. itching most common presenting complaint. (74%) primigravida. majority, 29 (58%), diagnosed between 34-35 weeks. 37.54 ± 1.96 weeks, 70% caesarean section. outcomes, 24 (48%) had fetal distress, 2 (4%) intrauterine growth restriction, 20(40%) meconium-stained liquor, demise, 7(14%) low birth weight babies,16.7% poor APGAR score 14 needed intensive care admission. alanine aminotransferase (ALT) higher among those adverse cut-off value 93.5 by ROC analysis.
 Conclusion: leads outcomes. Although no definite marker can rule out risk increased fetomaternal surveillance active management induction labour protocols may reduce incidence of........